BDBM50518420 CHEMBL4555682

SMILES Cc1ccc(Cl)c(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc32)c1Cl

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518420   

TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50518420(CHEMBL4555682)
Affinity DataEC50:  56nMAssay Description:Positive allosteric modulation of human D1R expressed in HEK cells assessed as increase in dopamine-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50518420(CHEMBL4555682)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human D1R expressed in CHO cells assessed as increase in dopamine-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50518420(CHEMBL4555682)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat D1R expressed in HEK cells assessed as increase in dopamine-induced cAMP accumulation relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed