BDBM50518348 CHEMBL4582434

SMILES C\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(C#CCOc2ccccc2)c2c(N)ncnc12

InChI Key InChIKey=VQTMVCGQZMIGPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518348   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50518348(CHEMBL4582434)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-fused BTK (2 to 659 residues) expressed in baculovirus expression system using biotin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed