BDBM50518345 CHEMBL4439998

SMILES Nc1ncnc2n(nc(C#CCOc3ccccc3)c12)[C@@H]1CCCN(C1)C(=O)C(=C\C1CC1)\C#N

InChI Key InChIKey=JADSPPIWPBULLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518345   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50518345(CHEMBL4439998)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-fused BTK (2 to 659 residues) expressed in baculovirus expression system using biotin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed