BDBM50518185 CHEMBL4571977

SMILES CC(C)(O)c1ccc2OCc3ncccc3\C(=C\CCN3CC[C@](O)(c4ccc(Cl)cc4)C(C)(C)C3)c2c1

InChI Key InChIKey=ZGFJFBOLVLFLLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518185   

TargetC-C chemokine receptor type 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518185(CHEMBL4571977)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518185(CHEMBL4571977)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed