BDBM50518092 CHEMBL4439854

SMILES OC1=C(C(N(C1=O)c1ccc(Br)cc1F)c1cccc(Br)c1)C(=O)C1CC1

InChI Key InChIKey=LZRAWLGPIYPQSJ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50518092   

TargetC-C chemokine receptor type 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataIC50: 8.51E+3nMAssay Description:Antagonist activity at human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataIC50: 8.77E+3nMAssay Description:Antagonist activity at human TEV protease site linked CCR2b expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataIC50: 8.64E+3nMAssay Description:Antagonist activity at human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataIC50: 8.71E+3nMAssay Description:Antagonist activity at human TEV protease site linked CCR2b expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcriptio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50518092(CHEMBL4439854)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcriptio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed