BDBM50518069 CHEMBL4542050::US11479538, Example 22

SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ncc(s2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F

InChI Key InChIKey=JQJHRZJLIRYDBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50518069   

LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MGAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 2nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed