BDBM50518060 CHEMBL4455357

SMILES Cn1nc(cc1-c1cnc(nc1)N1CCc2cc(cc(N3CCCC3=O)c12)S(=O)(=O)Nc1c(F)cc(Cl)cc1F)C(F)(F)F

InChI Key InChIKey=VSZRYLHBOKTNBO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50518060   

LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human MGAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant mouse MGAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed