BDBM50518048 CHEMBL4462791

SMILES CCC(CC)n1c(Cc2cccs2)nc2cc(ccc12)C(=O)N[C@@H](CC(C)C)CC([O-])=O

InChI Key InChIKey=VCQKKZXFASLXAH-UHFFFAOYSA-M

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518048   

TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518048(CHEMBL4462791)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at APJ receptor (unknown origin) assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518048(CHEMBL4462791)
Affinity DataEC50:  224nMAssay Description:Agonist activity at APJ receptor (unknown origin) assessed as increase in beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518048(CHEMBL4462791)
Affinity DataEC50:  692nMAssay Description:Induction of APJ receptor (unknown origin) internalization by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed