BDBM50518047 CHEMBL4475589

SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=RKFGCZWTURNFPN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518047   

TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518047(CHEMBL4475589)
Affinity DataEC50:  0.288nMAssay Description:Agonist activity at human APJ receptor by saphenous vein contraction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518047(CHEMBL4475589)
Affinity DataEC50:  692nMAssay Description:Induction of human APJ receptor internalization by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518047(CHEMBL4475589)
Affinity DataEC50:  2.14E+3nMAssay Description:Agonist activity at human APJ receptor assessed as increase in beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed