BDBM505180 US11066409, Compound I-0039

SMILES CCc1cc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)cc1OC

InChI Key InChIKey=YEAPXGQYMHSZNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505180   

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505180(US11066409, Compound I-0039)
Affinity DataIC50: 10nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
US Patent