BDBM50517951 CHEMBL4453252

SMILES Cc1ccnc(NC(=O)c2ccsc2NC(=O)c2ccn3cnnc3c2)n1

InChI Key InChIKey=CZKRMLYDZFVQPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517951   

TargetDecaprenylphosphoryl-beta-D-ribose oxidase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50517951(CHEMBL4453252)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6-thioredoxin tagged Mycobacterium tuberculosis H37Rv DprE1 expressed in Escherichia coli BL21(DE3) using FPR as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50517951(CHEMBL4453252)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 30 mins by in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed