BDBM50517794 CHEMBL4459455

SMILES COc1ncc(cc1C)N1CCc2ncnc(-c3ccnc(OC4CCN(C)CC4)c3)c2C1

InChI Key InChIKey=IGXLILDZYBTDND-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517794   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50517794(CHEMBL4459455)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human PI3Kdelta using PIP2 as substrate after 35 to 40 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL