BDBM50517699 CHEMBL4443086

SMILES CCCCOC(=O)Cc1cc(Nc2nc(Nc3ccc(cc3)C(=O)NC3CC(C)(C)N([O])C(C)(C)C3)ncc2F)n[nH]1

InChI Key InChIKey=MLWHQHRPLFMZHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517699   

TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50517699(CHEMBL4443086)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of aurora A (unknown origin) using Kemptide as substrate after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50517699(CHEMBL4443086)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of aurora B (unknown origin) using Kemptide as substrate after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed