BDBM50517687 CHEMBL4526830

SMILES FC(F)(F)Cc1cc2c(ncnc2s1)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=VURGVRRUQDUOHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517687   

TargetLysine-specific histone demethylase 1A(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517687(CHEMBL4526830)
Affinity DataIC50: 692nMAssay Description:Inhibition of recombinant human LSD1 (172 to 852 residues) using biotin-labelled H3K4me2 (1 to 24 residues) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517687(CHEMBL4526830)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of MAOB (unknown origin) by Promega MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517687(CHEMBL4526830)
Affinity DataIC50: 8.27E+3nMAssay Description:Inhibition of MAOA (unknown origin) by Promega MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed