BDBM50517631 CHEMBL4442052

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC2CCC(CC2)C2CCCCC2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=MPSXRNMCCMRBQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50517631   

TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517631(CHEMBL4442052)
Affinity DataIC50: 915nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517631(CHEMBL4442052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517631(CHEMBL4442052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517631(CHEMBL4442052)
Affinity DataIC50: 100nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed