BDBM50517549 CHEMBL4554684

SMILES CC(C)CN1CCc2cccc3[nH]cc(C1c1ccc(\C=C\C(O)=O)cc1)c23

InChI Key InChIKey=FJOTVKIMZYPXQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517549   

TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50517549(CHEMBL4554684)
Affinity DataIC50: 3.98E+4nMAssay Description:Binding affinity to recombinant human GST-tagged ERalpha LBD expressed in baculovirus-infected insect cells by lantha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50517549(CHEMBL4554684)
Affinity DataIC50: 1.00E+4nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by in multiplexed cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed