BDBM50517547 CHEMBL4541014

SMILES COc1cc(Nc2ncnc3cc(sc23)-c2ccccc2)cc(OC)c1OC

InChI Key InChIKey=ZFLPXKSPNADKJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517547   

TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed