BDBM50517377 CHEMBL4445529

SMILES CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(O)=O)C(O)=O)C(=O)N(C)[C@@H](CC(O)=O)C(=O)N(C)[C@@H](Cc1cccc2ccccc12)C(N)=O

InChI Key InChIKey=BMZYXLWLLWZVBA-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50517377   

TargetCholecystokinin receptor type A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50517377(CHEMBL4445529)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandPNGBDBM50517377(CHEMBL4445529)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandPNGBDBM50517377(CHEMBL4445529)
Affinity DataIC50: 603nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50517377(CHEMBL4445529)
Affinity DataIC50: 0.115nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed