BDBM50517296 CHEMBL4473739

SMILES [H][C@]12C[C@@]1(CO)[C@@H](O)[C@@H](O)[C@@H]2n1cnc(n1)C(N)=O

InChI Key InChIKey=NBDHEWVPZVSZLX-UHFFFAOYSA-N

Data  6 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50517296   

TargetAdenosine receptor A1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataEC50:  2.46E+3nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in CHOKI cells assessed as induction of beta-arrestin2 recruitment after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataIC50: 87nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP production after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataEC50:  758nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  495nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  1.91E+3nMAssay Description:Inhibition of 5HT2B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibition of sigma receptor 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  2.35E+3nMAssay Description:Inhibition of 5HT2C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50517296(CHEMBL4473739)
Affinity DataKi:  6.61E+3nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed