BDBM50517285 CHEMBL4572962

SMILES COc1nc(N[C@H]2CC[C@@H](CC2)NS(=O)(=O)CCC(C)C)nc2[nH]nc(N3CCOC[C@H]3C)c12

InChI Key InChIKey=VZBBAPFIHSZTRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517285   

TargetCyclin-dependent kinase 4(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50517285(CHEMBL4572962)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK4 by kinobeads-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50517285(CHEMBL4572962)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50517285(CHEMBL4572962)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed