BDBM50516819 CHEMBL4571010

SMILES CC(C)n1nc(C#Cc2cccc3c(Nc4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)nccc23)c2c(N)ncnc12

InChI Key InChIKey=NFIQFIOBFMDWIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516819   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50516819(CHEMBL4571010)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant His-tagged BRAF V600E mutant (unknown origin) (444-723 residues) expressed in Escherichia coli BL21(DE3)-RIL using MEKK97R ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed