BDBM50516768 CHEMBL4456822

SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc4cc(Cl)ccc4n3Cc3ccc(F)cc3)c2c1

InChI Key InChIKey=MOKOWIRMYMOJLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516768   

TargetProstaglandin G/H synthase 1(Sheep)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50516768(CHEMBL4456822)
Affinity DataIC50: 407nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate incubated for 5 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50516768(CHEMBL4456822)
Affinity DataIC50: 23nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate incubated for 5 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed