BDBM50516767 CHEMBL4591824

SMILES Clc1ccc(CN2CCN(CC2)C(=O)c2cc3cc(Cl)ccc3n2Cc2ccc(Cl)cc2)cc1

InChI Key InChIKey=SYSVNAHCFMMHPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516767   

TargetProstaglandin G/H synthase 1(Sheep)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50516767(CHEMBL4591824)
Affinity DataIC50: 361nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate incubated for 5 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50516767(CHEMBL4591824)
Affinity DataIC50: 32nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate incubated for 5 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed