BDBM50516760 CHEMBL4526356

SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(cc3C[C@@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@@]21[H])B(O)O

InChI Key InChIKey=FIAYIYKWRBIBQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50516760   

TargetEstrogen receptor(Human)
S£O Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50: 4.10nMAssay Description:Selective estrogen receptor down regulator activity at ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
S£O Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50: 4.10nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
S£O Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50: 13nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
S£O Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50: 7.80nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed