BDBM50516569 CHEMBL4585198::US10899738, Cpd. No 148

SMILES CCN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1

InChI Key InChIKey=MIDBFVUJIVFIOM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516569   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50516569(CHEMBL4585198 | US10899738, Cpd. No 148)
Affinity DataIC50: 6nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50516569(CHEMBL4585198 | US10899738, Cpd. No 148)
Affinity DataIC50: 6nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50516569(CHEMBL4585198 | US10899738, Cpd. No 148)
Affinity DataKi:  1nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed