BDBM50516557 CHEMBL4537683::US10899738, Cpd. No 55

SMILES N#Cc1ccc(cc1)N1CCC(CC1)N1CCC(CC1)C1(NCCc2ccccc12)C1CCCC1

InChI Key InChIKey=CIOJAPDJRIHTLV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516557   

TargetMenin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516557BDBM50516557(CHEMBL4537683 | US10899738, Cpd. No 55)
Affinity DataKi:  207nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516557BDBM50516557(CHEMBL4537683 | US10899738, Cpd. No 55)
Affinity DataIC50: 650nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516557BDBM50516557(CHEMBL4537683 | US10899738, Cpd. No 55)
Affinity DataIC50: 669nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent