BDBM50516083 CHEMBL4470490

SMILES CSc1ccccc1[C@H]2CCCN2C(=O)CNC(=O)NCc3ccc4c(c3)[C@H]5C[C@@H](N4)[C@@H](CO5)O

InChI Key InChIKey=BICVGZIZTMOLHN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516083   

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50: 4nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed