BDBM50516023 CHEMBL4466519

SMILES CNC(=O)Nc1ccc(cc1)-c1ncc2N(CC3CC3)C(=O)[C@]3(C)COCCN3c2n1

InChI Key InChIKey=YYVSGNQVBXYPOF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516023   

TargetSerine/threonine-protein kinase mTOR(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50516023(CHEMBL4466519)Copy SMILESCopy InChI

Affinity DataIC50: 7.90nMAssay Description:Inhibition of human mTOR measured after 30 mins in presence of ATP by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50516023(CHEMBL4466519)Copy SMILESCopy InChI

Affinity DataIC50: 79nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL