BDBM50515761 CHEMBL4533705

SMILES OC(Cn1cc(\C=C2/C(=O)Nc3ccccc23)c2ccccc12)Cn1c2ccccc2c(=O)c2ccccc12

InChI Key InChIKey=DTINRFLXDFJJLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515761   

TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515761(CHEMBL4533705)
Affinity DataIC50: 100nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed