BDBM50515759 CHEMBL4467394

SMILES CC1=NN(C(=O)\C1=C/c1cn(CC(O)Cn2c3ccccc3c(=O)c3ccccc23)c2ccccc12)c1cccc(Cl)c1

InChI Key InChIKey=DAMLVVVYOVXKIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515759   

TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515759(CHEMBL4467394)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed