BDBM50515653 CHEMBL4472508
SMILES CC(C)(C[C@H]1CN(c2cc(ccc2O1)-c1cc(F)cc(OC(F)F)c1)S(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O
InChI Key InChIKey=GULSIMHVQYBADX-UHFFFAOYSA-N
Data 14 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50515653
Affinity DataEC50: 102nMAssay Description:Transactivation of human GAL4-fused RORgammaT LBD expressed in human HEK293T cells incubated for 16 to 20 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at APC-labeled biotinylated RORgammaT LBD (unknown origin) assessed as induction of biotinylated SRC-1 peptide recruitment incubated...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at ROR-gammat (unknown origin) by dual FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human His-tagged RORgamma-LBD expressed in Sf9 cells assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitm...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at RORgamma in human whole blood assessed as increase in IL-17A productionMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human ROR-gamma LBD expressed in HEK293 cells assessed as transcriptional activity in presence of ursolic acid by Gal4-luciferase...More data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Agonist activity at human PXR-gamma expressed in HEK293 cells assessed as transcriptional activity in presence of ursolic acid by Gal4-luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RORalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RORbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at biotinylated APC-labeled RORgammat LBD (unknown origin) assessed as increase in recruitment of europium-labeled SRC1 coactivator ...More data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:Agonist activity at human Gal4-fused RORgamma expressed in HEK293T cells assessed as luciferase activity incubated for 16 to 20 hrs by Luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 2.93E+3nMAssay Description:Agonist activity at human Gal4-fused RORalpha expressed in HEK293T cells assessed as luciferase activity incubated for 16 to 20 hrs by Luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 5.43E+3nMAssay Description:Agonist activity at human Gal4-fused RORbeta expressed in HEK293T cells assessed as luciferase activity incubated for 16 to 20 hrs by Luciferase repo...More data for this Ligand-Target Pair