BDBM50515532 CHEMBL4515694

SMILES COc1ccc(cc1OC)C(N(C1CC1)C(=O)\C=C\C(=O)c1ccc(C)cc1)C(=O)NC(C)(C)C

InChI Key InChIKey=GTENTLZUYBDEIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515532   

TargetThioredoxin reductase 1, cytoplasmic(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515532(CHEMBL4515694)
Affinity DataIC50: 7.66E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed