BDBM50515504 CHEMBL4453429

SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)Cn1cnc(n1)[N+]([O-])=O

InChI Key InChIKey=VOQPJMGPHUWKCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515504   

TargetVascular endothelial growth factor receptor 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50515504(CHEMBL4453429)
Affinity DataIC50: 87nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using FAM-22 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50515504(CHEMBL4453429)
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using FAM-22 pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed