BDBM50515347 CHEMBL4461759

SMILES Cc1cc(-c2ccc(\C=C3/C(=O)N(N=C3C3CC3)c3ccc(cc3)C(O)=O)s2)c(cc1C)C(F)(F)F

InChI Key InChIKey=BOFPSWBVJMVDJI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50515347   

TargetHistone deacetylase 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 160nMAssay Description:Inhibition of p300 (unknown origin) using biotinylated histone H3 (1 to 21 residues) as substrate measured after 90 mins in presence of Acetyl CoA by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50515347(CHEMBL4461759)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed