BDBM50515315 CHEMBL4527908

SMILES Cc1cccc(n1)-c1nn(CC(=S)Nc2cccc(F)c2)cc1-c1ccc2nsnc2c1

InChI Key InChIKey=TVWMUKRZUMLJMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515315   

TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515315(CHEMBL4527908)
Affinity DataIC50: 7.04E+3nMAssay Description:Inhibition of human recombinant untagged p38alpha expressed in Escherichia coli using ATF2 as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515315(CHEMBL4527908)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515315(CHEMBL4527908)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515315(CHEMBL4527908)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed