BDBM50515259 CHEMBL4470981

SMILES Fc1ccc2NC(=O)\C(=C3/S\C(NC3=O)=N/c3ccccc3Cl)c2c1

InChI Key InChIKey=HNOFQKYBQYGFNQ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50515259   

TargetMitogen-activated protein kinase 8(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human JNK1alpha1 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of recombinant human Abl (27 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma33P]ATP by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human Abl Y253F mutant (27 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human JNK2alpha2 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant human full-length yes using poly(Glu, Tyr) 4:1 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant human Abl Q252H mutant (27 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full-length JNK3 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed