BDBM50515220 CHEMBL4544781

SMILES Nc1ncnc2n(cnc12)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)C1(F)F

InChI Key InChIKey=XSXKATMUCWUUFZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50515220   

TargetAdenosylhomocysteinase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human placental SAH hydrolase expressed in Escherichia coli JM109 using SAH as substrate preincubated for 10 mins followed by SAH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataEC50:  260nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human placental SAH hydrolase expressed in Escherichia coli JM109 using SAH as substrate preincubated for 10 mins followed by SAH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed