BDBM50515217 CHEMBL4516236

SMILES C[C@H]1COCCN1c1nc(cc(n1)-c1cnc(N)nc1C(F)F)N1CCOCC1

InChI Key InChIKey=NKNDEDRTGFKLFD-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515217   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50515217(CHEMBL4516236)Copy SMILESCopy InChI

Affinity DataKi:  4.10nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant N-terminal His6-tagged PI3K p110alpha (unknown origin) incubated for 1 hr by FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50515217(CHEMBL4516236)Copy SMILESCopy InChI

Affinity DataKi:  15nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant human C-terminal GST-tagged mTOR (1360 to 2549 amino acids) expressed in insect...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL