BDBM50515213 CHEMBL4539743

SMILES Nc1cc(c(cn1)-c1nc(nc(n1)N1C2CCC1COC2)N1C2CCC1COC2)C(F)(F)F

InChI Key InChIKey=KCQYFZPZEHOMAB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515213   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50515213(CHEMBL4539743)
Affinity DataKi:  77nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant human C-terminal GST-tagged mTOR (1360 to 2549 amino acids) expressed in insect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandPNGBDBM50515213(CHEMBL4539743)
Affinity DataKi:  4.64E+3nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant N-terminal His6-tagged PI3K p110alpha (unknown origin) incubated for 1 hr by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed