BDBM50515207 CHEMBL4453300

SMILES Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1C2CCC1COC2)C(F)(F)F

InChI Key InChIKey=CIMGIKRGAYTHPE-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515207   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50515207(CHEMBL4453300)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant N-terminal His6-tagged PI3K p110alpha (unknown origin) incubated for 1 hr by FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50515207(CHEMBL4453300)Copy SMILESCopy InChI

Affinity DataKi:  43nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant human C-terminal GST-tagged mTOR (1360 to 2549 amino acids) expressed in insect...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL