BDBM50514988 CHEMBL4548654

SMILES CN1CCC(CC(=O)Nc2nnc(s2)N2CC[C@H](C2)Nc2nnc(NC(=O)Cc3ccccc3)s2)CC1

InChI Key InChIKey=CNSWGIVZVOQWGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514988   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514988(CHEMBL4548654)
Affinity DataIC50: 244nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed