BDBM50514975 CHEMBL4473143

SMILES O=C(Cc1ccccc1)Nc1nnc(NC[C@H]2CCN(C2)c2nnc(NC(=O)Cc3ccccc3)s2)s1

InChI Key InChIKey=LQZZAPPZBNMHEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514975   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed