BDBM50514822 CHEMBL4441037
SMILES COc1ccc(NC(=O)C=C)cc1Nc1cc(ccn1)-c1c(nc(SC)n1C)-c1ccc(F)cc1
InChI Key InChIKey=HOFOJIJWCUWXQJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50514822
Affinity DataIC50: 111nMAssay Description:Inhibition of human EGFR L858R/T790M mutant using poly[Glu:Tyr] (4:1) as substrate measured in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human EGFR L858R/T790M/C797S mutant using poly[Glu:Tyr] (4:1) as substrate measured in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair