BDBM50514822 CHEMBL4441037

SMILES COc1ccc(NC(=O)C=C)cc1Nc1cc(ccn1)-c1c(nc(SC)n1C)-c1ccc(F)cc1

InChI Key InChIKey=HOFOJIJWCUWXQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514822   

TargetEpidermal growth factor receptor(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514822(CHEMBL4441037)
Affinity DataIC50: 111nMAssay Description:Inhibition of human EGFR L858R/T790M mutant using poly[Glu:Tyr] (4:1) as substrate measured in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514822(CHEMBL4441037)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human EGFR L858R/T790M/C797S mutant using poly[Glu:Tyr] (4:1) as substrate measured in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed