BDBM50514811 CHEMBL4564658

SMILES CSc1nnc(CO)n1-c1ccc(Cl)cc1Cl

InChI Key InChIKey=SLJNFNZLYXHRAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514811   

TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514811(CHEMBL4564658)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed