BDBM50514745 CHEMBL4439953

SMILES CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1

InChI Key InChIKey=GDBRUKFBBFJPAM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514745   

TargetNischarin(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514745(CHEMBL4439953)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514745(CHEMBL4439953)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed