BDBM50514721 CHEMBL4450506

SMILES CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1)c1ccccc1

InChI Key InChIKey=AOHIJBRGGKXQOP-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50514721   

TargetCholecystokinin receptor type A(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataIC50: 5.94E+3nMAssay Description:Displacement of [125I]CCK-8s from human CCKA incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]CCK-8s from human CCKB incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNischarin(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataIC50: 9.12E+5nMAssay Description:Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNischarin(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50514721(CHEMBL4450506)
Affinity DataKi:  9.12E+5nMAssay Description:Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed