BDBM50514688 CHEMBL4590860::US20240150396, Compound 6

SMILES [O-][N+](=O)c1ccc(\C=C\[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1

InChI Key InChIKey=VICYRHHEPALLBZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514688   

TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50514688(CHEMBL4590860 | US20240150396, Compound 6)
Affinity DataKi:  370nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as rate constant for enzyme-inhibitor-substrate complex using Cbz-Phe-Arg-AMC as substrate measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50514688(CHEMBL4590860 | US20240150396, Compound 6)
Affinity DataKi:  370nMAssay Description:All enzyme assays were performed at 25° C. Initial rates of the peptidolytic reaction catalyzed by cruzain were measured by monitoring the fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent