BDBM50514514 CHEMBL4563120

SMILES COc1ccc(cn1)-c1cnc(Nc2ccc(cc2)N2CCN(C)CC2)nc1Nc1ccccc1NC(=O)C=C

InChI Key InChIKey=WAEYWKWSXPSJHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514514   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514514(CHEMBL4563120)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of tracer 222 binding to recombinant human His-tagged TAK1 (437 to 504 residues) expressed in baculovirus expression system using tyrosine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514514(CHEMBL4563120)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human His-tagged full length SRC expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514514(CHEMBL4563120)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) expressed in baculovirus expression system using tyrosine-4 peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed