BDBM50514513 CHEMBL4562024

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(c(Nc3ccccc3NC(=O)C=C)n2)-c2ccc(cc2)C(C)=O)cc1

InChI Key InChIKey=QZCDUPGTUBPMMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514513   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514513(CHEMBL4562024)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of tracer 222 binding to recombinant human His-tagged TAK1 (437 to 504 residues) expressed in baculovirus expression system using tyrosine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514513(CHEMBL4562024)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human His-tagged full length SRC expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514513(CHEMBL4562024)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) expressed in baculovirus expression system using tyrosine-4 peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed