BDBM50514491 CHEMBL4556003

SMILES CCCCCc1ccc(cc1)S(=O)(=O)C1C(NCc2ccc3ccccc3c2)C2CC(CNC3CCCC3)C1N2

InChI Key InChIKey=SFYSZVJXKDRKMX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50514491   

TargetPlasmepsin II(Plasmodium falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514491(CHEMBL4556003)
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514491(CHEMBL4556003)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514491(CHEMBL4556003)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514491(CHEMBL4556003)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514491(CHEMBL4556003)
Affinity DataIC50: 7.55E+3nMAssay Description:Inhibition of human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed